Human Rights Watch, a global organization well known for fighting torture, among other things, has taken up the issue of global pain lately. Diederik Lohman, a senior researcher with Human Privileges Watch, said he has spoken with patients who have informed him they commit suicide as the pain was basically unbearable. It’s a significant leap, from campaigning about torture to campaigning about a drug like morphine, isn’t it? asked Simon.. A world of pain For most people in the developed world, painkillers for disease or for recovery from medical procedures certainly are a prescription away just.Editing is a process where RNA is changed after it is produced from DNA, resulting in an altered gene product. This RNA editing is likely to play a role in the forming of tumours by either inactivating a tumour suppressor or activating genes that promote tumour progression. Within their study, the NUS researchers found that the RNA editing enzyme ADAR1, which catalyses the editing process, is over-expressed in ESCC tumours significantly. They noticed that ADAR1 changes the product of the AZIN1 protein to an application which promotes the development of the condition. Clinically, the tumoural over-expression of ADAR1 was correlated with the shorter survival time of ESCC sufferers. The findings suggest that ADAR1 can serve as a useful biomarker to detect disorders resulting in ESCC and as a potential therapeutic target.