In the journal paper.

In the journal paper, the University of Utah researchers report .* They have found a way to delete or make duplicate moderately long to very long pieces of DNA and these mutations may occur much more frequently than other methods. This makes it easier to find out what defects or diseases that occur due to such mutations, and thus what the DNA does normally. Cells, developed a much more efficient method for mixing and recombining pieces of two chromosomes, making it easier to breed mice with human cancers. Such mice are develop new therapies.

The new method is a faster, cheaper way to mutate DNA, costs $ 200 for each mouse with a mutant gene or other DNA sequence to create, even though the savings are not adequate because more mutant mice must obtain bred desired mutants, he says.

In their study demonstrated Wu and Capecchi, that involved the use of a gene for a mouse jumping gene in bone formation the result mutate mutant mice with abnormally short limbs and tail.###Contacts:* Mario Capecchi, distinguished professor and co-chairman of the Human Genetics* Sen Wu, a postdoctoral fellow in human genetics* Lee Siegel, science news specialist, University of Utah Public RelationsUniversity of Utah Public Relations 201 Presidents Circle, Room 308 Salt Lake City, Utah 84112-9017University of Utah Health Sciences Center Office of Public Affairs 420 Chipeta Way, Suite 1900 Salt Lake City..####Editor’s Note: This study was developed by the Department of Dermatology, University of California, in San Francisco, and a Dermatology Foundation a dermatologist Investigator research fellow (Dr. Of this study did not receive any funding from a pharmaceutical company. Please refer to the cloth for further information , including other History, writer contributions and affiliations, financial disclosures, financing and assistance.

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