Tommaso Sanna.

Tommaso Sanna, M.D http://viagra-danmark.net ., Hans-Christoph Diener, M.D., Ph.D., Rod S. Passman, M.D., M.S.C.E., Vincenzo Di Lazzaro, M.D., Richard A. Bernstein, M.D., Ph.D., Carlos A. Morillo, M.D., Marilyn Mollman Rymer, M.D., Vincent Thijs, M.D., Ph.D., Tyson Rogers, M.S., Frank Beckers, Ph.D., Kate Lindborg, Ph.D., and Johannes Brachmann, M.D. For the CRYSTAL AF Investigators: Cryptogenic Stroke and Underlying Atrial Fibrillation Ischemic stroke is one of the leading causes of death and disability.1 The reason remains to be unexplained after routine evaluation in 20 to 40 percent of cases, leading to the classification, by exclusion, of cryptogenic stroke.2-6 Atrial fibrillation is a well-recognized reason behind ischemic stroke,7 although risk is markedly reduced by anticoagulation7,8 Documentation of atrial fibrillation must initiate anticoagulant therapy after ischemic stroke.8 In the lack of documented atrial fibrillation, antiplatelet agents are recommended.7 Given the paroxysmal and asymptomatic character of atrial fibrillation often, it may not be detected with the use of traditional monitoring techniques.9-12 Strategies for recognition of atrial fibrillation have included in-hospital monitoring,13 serial electrocardiography ,14,15 Holter monitoring,16 monitoring with the use of external loop or event recorders,17-22 long-term outpatient monitoring,23-28 and monitoring through insertable cardiac monitors ,29-31 yielding detection rates which range from 0 to 25 percent.

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