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Vesta Richardson, M silagra pills .D., Joselito Hernandez-Pichardo, M.D., Manjari Quintanar-Solares, M.D., Marcelino Esparza-Aguilar, M.D., Brian Johnson, B.S., Cesar Misael Gomez-Altamirano, M.D., Umesh Parashar, M.D., M.P.H., and Manish Patel, M.D.: Aftereffect of Rotavirus Vaccination on Death from Childhood Diarrhea in Mexico Despite the improved basic safety of food, water, and sanitation and the aggressive promotion of non-invasive interventions and prevention strategies , diarrhea continues to be the second leading infectious cause of childhood death world-wide, accounting for 1 approximately.8 million annual deaths in children under 5 years of age.1 Rotavirus is the single most important cause of serious childhood diarrhea globally and annually causes over fifty % a million deaths among children under 5 years of age.2,3 In a large clinical trial conducted in Latin America, the monovalent human rotavirus vaccine Rotarix showed a protective efficacy of 85 percent against severe rotavirus disease and of 42 percent against severe diarrhea from any cause.4-7 Based on these encouraging data, several countries in the Americas began including a rotavirus vaccine in their routine childhood immunization program in 2006.8,9 In Mexico, significant reductions in diarrhea-related deaths and complications occurred from 1990 to 2002 as a result of improved sanitation and secure water, the promotion of breast-feeding and oral rehydration, and supplementation with a megadose of vitamin A.10-12 These measures have reduced the amount of diarrhea-related deaths occurring in the springtime and summer months that were attributable to bacterial pathogens, but deaths during the fall and winter season, once the prevalence of rotavirus is increased, have persisted.10 Due to the persistent burden of diarrhea-related deaths and hospitalizations from rotavirus, in 2006, Mexico became one of the initial countries worldwide to introduce the monovalent rotavirus vaccine in its national immunization program.

Bravata, M.D., Pamela W. Duncan, Ph.D., Barbara H. Corn, Ph.D., Alysia D. Maffucci, J.D., Stephen E. Nadeau, M.D., Susan S. Conroy, D.Sc., P.T., Janet M. Powell, Ph.D., Grant D. Huang, Ph.D., and Peter Peduzzi, Ph.D.: Robot-Assisted Therapy for Long-Term Upper-Limb Impairment after Stroke.. Albert C. Lo, M.D., Ph.D., Peter D. Guarino, M.P.H., Ph.D., Lorie G. Richards, Ph.D., Jodie K. Haselkorn, M.D., M.P.H., George F. Wittenberg, M.D., Ph.D., Daniel G. Federman, M.D., Robert J. Ringer, Pharm.D., Todd H. Wagner, Ph.D., Hermano I. Krebs, Ph.D., Bruce T. Volpe, M.D., Christopher T.

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